Endocrine Abstracts

Introduction: The question if obesity may protect against osteoporosis is still a matter of discussion. A breakthrough in this debate may be the introduction of a state-of-the-art densitometric software (CoreScan) suitable for fast and accurate volumetry of total body fat (BF), including android (A), female-type (F) and visceral fat (VAT) volumes.Aim: The aim of the study was to analyze an association between bone mineral density (BMD]), concentrations o...

Obesity is an independent risk factor for the development of cardiovascular disease, frequently associated with various metabolic disorders defined as metabolic syndrome. High plasma total homocysteine (Hcy) concentration is now well established as a powerful risk indicator for a wide range of vascular diseases.The aim of this study was to investigate total Hcy levels in obese children and their possible association with both metabolic syndrome and vario...

Introduction: The prevalence of incidentally found adrenal tumors – adrenal incidentalomas (AI) – in imaging procedures and autopsy series is up to 4.5–8.7%. Endocrine and clinical evaluation is carried out to diagnose hormonal function or malignancy of the tumors. Nonfunctional adenomas comprise about 80% of AI. The aim of the study was to identify possible association between various clinical, hormonal and radiological features of nonfunctional AI.<p class...

Introduction: Reduced bone mineral density (BMD) is present in many women with Turner syndrome (TS), while hypo-estrogenism is known to play a vital role in bone mineralization disturbances. It has been suggested that genetic factors play an important role in the regulation of BMD. The aim of this study was to analyze the association between PvuII and XbaI ER-a polymorphisms and BMD in TS patients subjected to estroprogestagen (EP) treatment.Material and...

Introduction: The aim of this study was to verify if genetic factors influence the short- and long-term therapeutic responses to oestroprogestagen (OP) therapy, implemented in girls with functional hypothalamic amenorrhoea (FHA) in order to improve their bone mineral density (BMD).Material and methods: The study included 84 FHA girls who underwent a 4-year sequential OP therapy with 17-β oestradiol and didrogesterone. Changes in the lumbar spine BMD...

Introduction: Neuroendocrine cancer of the ampulla of Vater area belongs to the most rare GEP-neuroendocrine tumors (NET). In the literature, there are few reports of extremely malignant course of this cancer. Among 242 patients with NET from the Department of Endocrinology in 2009–2013, 58 pancreatic NET were discovered, among which seven patients had neuroendocrine cancer of the ampulla of Vater. The aim of this study was to determine the clinical characteristics, stagi...